Test benches, physical simulators and reference artefacts are essential for experimental development, calibration, performance, validation and conformity assessment of biomedical measurement methods and instrumentation. Nevertheless, their metrological characterization, traceability, reproducibility and ability to represent the intended biological measurands remain open challenges.

This Special Session will provide an interdisciplinary forum for advances in the design, implementation, functional testing and metrological characterization of biomedical measurement methods and instruments in diagnostics and therapy. Contributions are invited on sensors and acquisition systems, test benches, physical simulators, tissue-mimicking and smart materials, reference artefacts, physiological flow loops, biomechanical test rigs, sensorized phantoms and dedicated calibration facilities. Contributions addressing mechanical, acoustic, thermal, electrical, optical and fluid-dynamic characterization are encouraged.

This Session will focus on measurand definition, instrumentation design, calibration and validation strategies, static and dynamic characterization, metrological traceability, measurement uncertainty, influence quantities, sensitivity, repeatability, reproducibility and interlaboratory comparability. Applications include diagnostic imaging, ultrasound and Doppler systems, cardiovascular and musculoskeletal assessment, wearable and contactless devices, biomechanical measurements and instrumentation, and therapeutic equipment. By connecting biomedical metrology, experimental mechanics and measurement of human functions, the Session aims to advance experimentally validated methods, reference instrumentation and test protocols. The expected outcome is a multidisciplinary discussion on traceable and uncertainty-aware validation frameworks capable of supporting research, quality assurance, regulatory evaluation and clinical translation.